Cell-specific drug transfer from liposomes bearing monoclonal antibodies

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

S Ohkuma, Brian D. Poole · Proceedings of the National Academy of Sciences · 1978 · 2.2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Targeting to cells of fluorescent liposomes covalently coupled with monoclonal antibody or protein A

Lee Leserman, Jacques Barbet, F. M. Kourilsky et al. · Nature · 1980 · 387 citations

Pharmacy, Cell Biology, Molecular Pharmaceutics +14

Antibody-mediated targeting of liposomes. Binding to lymphocytes does not ensure incorporation of vesicle contents into the cells

John N. Weinstein, Robert Blumenthal, Susan O. Sharrow et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1978 · 90 citations

Life Sciences, Cell Biology, Immunology +10

Receptor-mediated endocytosis of antibody-opsonized liposomes by tumor cells.

Lee Leserman, John N. Weinstein, Robert Blumenthal et al. · Proceedings of the National Academy of Sciences · 1980 · 81 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Kinetics of antibody-dependent binding of haptenated phospholipid vesicles to a macrophage-related cell line

J. Todd Lewis, Dean G. Hafeman, Harden M. McConnell · Biochemistry · 1980 · 46 citations

Life Sciences, Biochemistry, Immunology +14