Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu et al. · Science · 1994 · 4.1K citations

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Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

Joshua B. Bederson, L H Pitts, Masahiko Tsuji et al. · Stroke · 1986 · 2.7K citations

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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Martin Göttlicher · The EMBO Journal · 2001 · 1.9K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen

Christopher J. Phiel, Fang Zhang, Eric Yi‐Hsiu Huang et al. · Journal of Biological Chemistry · 2001 · 1.7K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Amphetamine, Haloperidol, and Experience Interact to Affect Rate of Recovery After Motor Cortex Injury

Dennis M. Feeney, A. Celada Gonzalez, Wendy Law · Science · 1982 · 920 citations

Medicine, Neuroscience, Pharmacology +17