Concepedia

Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells

Sai T. Reddy, Xin Ge, Aleksandr E. Miklos, Randall A. Hughes, Seung Hyun Kang, Kam Hon Hoi, Constantine Chrysostomou, Scott Hunicke‐Smith, Brent L. Iverson, Philip W. Tucker,

Nature Biotechnology · 2010 · 302 citations · 26 references

DOI

Concepts

References

26

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

, , +11

Next-generation DNA sequencing

Jay Shendure, Hanlee P. Ji · Nature Biotechnology · 2008 · 4.5K citations

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

Xavier Brochet, Marie‐Paule Lefranc, Véronique Giudicelli · Nucleic Acids Research · 2008 · 1.3K citations · Full text

, , +17

Making antibody fragments using phage display libraries

Tim Clackson, Hennie R. Hoogenboom, Andrew D. Griffiths et al. · Nature · 1991 · 1.2K citations

, , +14

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

Jens Wrammert, Kenneth G. C. Smith, Joe Miller et al. · Nature · 2008 · 1.1K citations · Full text

, , +16