Kinetics and Mechanism of the Pyridinolyses of Dimethyl Phosphinic and Thiophosphinic Chlorides in Acetonitrile

Abstract

1 the reactions of dimethyl phosphinic (Me2P(=O)Cl; 1O) and thio- phosphinic (Me2P(=S)Cl; 1S) chlorides with substituted (X) pyridines are investigated kinetically in acetonitrile (MeCN) at -25.0 and 35.0 o C, respectively (eq 1) to clarify the phosphoryl transfer mechanism, as well as to compare the pyridinolyses of diphenyl phosphinic (Ph2P(=O)Cl; 2O) and thiophosphinic (Ph2P(=S)Cl; 2S) chlorides. 1d