Opioids act at μ-receptors to hyperpolarize arcuate neurons via an inwardly rectifying potassium conductance

Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.

Henry I. Mosberg, R. P. Hurst, Victor J. Hruby et al. · Proceedings of the National Academy of Sciences · 1983 · 739 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

R A North, John T. Williams, Annmarie Surprenant et al. · Proceedings of the National Academy of Sciences · 1987 · 618 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Analogues of β-LPH61–64 posessing selective agonist activity at μ-opiate receptors

B.K. Handa, Anthony C. Lane, John A.H. Lord et al. · European Journal of Pharmacology · 1981 · 507 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Inward rectification of resting and opiate-activated potassium currents in rat locus coeruleus neurons

JT Williams, RA North, Takayuki Tokimasa · Journal of Neuroscience · 1988 · 170 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Opiate-receptor interactions on single locus coeruleus neurones.

John T. Williams, R. Alan North · Molecular Pharmacology · 1984 · 168 citations

Medicine, Neuroscience, Pharmacology +17