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Simultaneous regeneration of articular cartilage and subchondral bone induced by spatially presented TGF-beta and BMP-4 in a bilayer affinity binding system

Tissue EngineeringRegenerative MedicineMechanobiologyEngineeringBone Morphogenic ProteinBone RepairOsteoarthritisBone RemodelingArticular CartilageBiomedical EngineeringSimultaneous RegenerationSubchondral BoneMedicineOrthopaedic SurgeryOsteocalcin