Concepedia

Regulation of the interferon‐α production induced by RNA‐containing immune complexes in plasmacytoid dendritic cells

Maija‐Leena Eloranta, Tanja Lövgren, Doreen Finke, Linda Mathsson, Johan Rönnelid, Berthold Kastner, Gunnar V. Alm, Lars Rönnblom

Arthritis & Rheumatism · 2009 · 127 citations · 39 references

DOI

Abstract

IFNalpha production induced by RNA-containing ICs in PDCs is regulated by a network of interactions between monocytes, NK cells, and PDCs, involving several pro- and antiinflammatory molecules. This should be considered when designing and applying new therapies.

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