5α-pregnan-3α-ol-20-one blocks nicotine-induced seizures and enhances paired-pulse inhibition

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

Maria Dorota Majewska, Neil L. Harrison, Rochelle D. Schwartz et al. · Science · 1986 · 2.2K citations

Medicine, Neuroscience, Pharmacology +17

Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex.

Neil L. Harrison, Monika Majewska, J W Harrington et al. · Journal of Pharmacology and Experimental Therapeutics · 1987 · 615 citations

Life Sciences, Neuroscience, Pharmacology +17

Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action.

Kelvin W. Gee, Michael B. Bolger, Roberta Dı́az Brinton et al. · Journal of Pharmacology and Experimental Therapeutics · 1988 · 467 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Effects of Glucocorticoids and Norepinephrine on the Excitability in the Hippocampus

Marian Joëls, E. R. de Kloet · Science · 1989 · 378 citations

Life Sciences, Neurobiology, Neuroscience +17

Anticonvulsant profile of the progesterone metabolite 5α-pregnan-3α-ol-20-one

Delia Belelli, Michael B. Bolger, Kelvin W. Gee · European Journal of Pharmacology · 1989 · 323 citations

Medicine, Endocrinology, Pharmacology +7