Optimized visualization of vessels in contrast enhanced intracranial MR angiography

Abstract

In this study, the problem of small vessel visualization in magnetic resonance angiography is addressed. The loss of vessel contrast due to slow flow-related signal saturation can be compensated by the T1 reduction obtained from the use of an MR contrast agent, such as Gd-DTPA. The vessel/background signal-difference-to-noise ratio (SDNR) is shown to strongly depend on the imaging parameters, as well as on the time course of the blood T1 values obtained from the contrast injection. Specifically, it was found that vessel SDNR increases almost linearly with TR, if the sampling bandwidth is reduced proportionately.