Interaction between prostacyclin and nitric oxide in the reflex control of the coronary circulation in conscious dogs

Abstract

Our results indicate that the coronary vasodilation induced by PGI2 was partially attenuated by NLA or atropine, suggesting that the coronary vasodilation induced by PGI2 is due to two components: a reflex parasympathetic cholinergic vasodilation mediated by NO and a direct action of PGI2.