Adaptative physico-chemistry of bio-related calcium phosphates

Abstract

The mineral/organic ratio, the crystal dimensions, the stoichiometry and the surface properties of biological apatites in various mineralized tissues are controlled and adapted to reach specific properties. We proposed a model of a structured hydrated layer, located at the surface of apatite nanocrystals, which comprises ionic non-apatitic environments responsible for nanocrystalline apatite reactivity and evolution (maturation, ion mobility and adsorption properties). Understanding this adaptative ability is useful in the design of treatments for bone diseases and also in the preparation of bioactive biomaterials for bone filling, replacement and reconstruction.