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Interleukin-6 in Tear Fluid After Photorefractive Keratectomy and Its Effects on Keratocytes in Culture

DOI

42

Citations

0

References

1997

Year

Fran ois Malecaze, Val rie Simorre, P. Chollet, Jeanne Leung Tack, M. Muraine, Dominique Le Guellec, Natalio Vita, J L Arné, Jean Marie Darbon
Cornea

Abstract

IL-6 stimulates collagen synthesis in general and collagen type I in particular. Furthermore, it reduces the production of MMP-2, the latent form of the metalloproteinase, by cultured keratocytes. The results suggest that IL-6 might be regarded as a mediator involved in corneal healing after excimer laser.