Synthetic Applications of Cyanotrimethylsilane, lodotrimethylsilane, Azidotrimethylsilane, and Methylthiotrimethylsilane

Abstract

Recent developments in the preparation and reactions of cyano-, iodo-, azido-, and methylthiotrimethylsilane are discussed. The synthetic utility of these reagents is illustrated by examples. 1. Cyanotrimethylsilane 1.1. Preparation 1.2. Cyanosilylation of Aldehydes, Ketones, and Schiff Bases 1.3. Miscellaneous Reactions 2. Iodotrimethylsilane 2.1. Preparation 2.2. Cleavage of Esters 2.3. Cleavage of Carbamates 2.4. Cleavage of Ethers 2.5. Reactions with Alcohols 2.6. Miscellaneous Reactions 3. Azidotrimethylsilane 4. Methylthiotrimethylsilane 5. Conclusions