Concepedia

Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression

Shu-Ching Hsieh, Jen‐Pi Tsai, Shun‐Fa Yang, Meng-Ju Tang, Yi‐Hsien Hsieh

Amino Acids · 2014 · 76 citations · 47 references

DOI

Concepts

References

47

Sorafenib in Advanced Hepatocellular Carcinoma

Josep M. Llovet, Sergio Ricci, Vincenzo Mazzaferro et al. · New England Journal of Medicine · 2008 · 13K citations · Full text

, , +12

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

Ann‐Lii Cheng, Yoon‐Koo Kang, Zhendong Chen et al. · The Lancet Oncology · 2008 · 5.8K citations

, , +11

Sorafenib in Advanced Hepatocellular Carcinoma

재연 정 · 2008 · 5.6K citations

, , +12

Hepatogastroenterology

Kinjiro Sumiyoshi, Norihiro Sato, Shin Akagawa et al. · Hepatogastroenterology · 2011 · 2.5K citations

, , +17

Diabetes and Cancer

Edward L. Giovannucci, David M. Harlan, Michael C. Archer et al. · Diabetes Care · 2010 · 2.2K citations · Full text

, , +14