Effect of transforming growth factor‐beta1 on expression of the connective tissue growth factor (<i>CCN2/CTGF</i>) gene in normal human gingival fibroblasts and periodontal ligament cells

Abstract

The expression of CCN2/CTGF mRNA and protein was induced by transforming growth factor-beta1 in human gingival fibroblasts and periodontal ligament cells. These results suggest that CCN2/CTGF plays an important role in wound healing and in the regeneration of periodontal tissue.