Studies on Synthetic Nucleosides. I. Trimethylsilyl Derivatives of Pyrimidines and Purines.

Abstract

Pyrimidine and purine bases were readily derived to trimethylsilyl derivatives by treatment with trimethylchlorosilane-triethylamine or hexamethyldisilazane. By the infrared investigation, it was clarified that the obtained derivatives possessed aromatic ring systems and physical properties of the product were reported.