Attenuation of a Brucella abortus mutant lacking a major 25 kDa outer membrane protein in cattle

Abstract

The 25 kd outer membrane protein may be an important virulence factor for B. abortus in cattle. The attenuation of the Omp25 mutant in cattle may involve the inability of BA25 to replicate efficiently in bovine phagocytes and chorionic trophoblasts.