Protein aging: Truncation of aquaporin 0 in human lens regions is a continuous age-dependent process

Massive increase in the stiffness of the human lens nucleus with age: the basis for presbyopia?

Karl R. Heys, Sandra Leigh Cram, Roger J.W. Truscott · PubMed · 2004 · 302 citations · Full text

Health Professions, Ophthalmology, Physics +13

Age-Related Changes in Human Crystallins Determined from Comparative Analysis of Post-translational Modifications in Young and Aged Lens:  Does Deamidation Contribute to Crystallin Insolubility?

Phillip A. Wilmarth, Stephen Tanner, Surendra Dasari et al. · Journal of Proteome Research · 2006 · 289 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Mutations in the founder of the MIP gene family underlie cataract development in the mouse

Alan Shiels, Steven Bassnett · Nature Genetics · 1996 · 279 citations

Medicine, Genetics, Molecular Genetics +10

The channel architecture of aquaporin 0 at a 2.2-Å resolution

William Harries, David Akhavan, Larry J. W. Miercke et al. · Proceedings of the National Academy of Sciences · 2004 · 267 citations

Life Sciences, Biology, Biophysics +17

Water Channel Properties of Major Intrinsic Protein of Lens

S.M. Mulders, Gregory M. Preston, Peter M.T. Deen et al. · Journal of Biological Chemistry · 1995 · 250 citations · Full text

Natural Sciences, Biochemistry, Physiology +17