Regulation of G proteins by chronic morphine in the rat locus coeruleus

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

Paul C. Sternweis, Janet D. Robishaw · Journal of Biological Chemistry · 1984 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine

George K. Aghajanian · Nature · 1978 · 800 citations

Medicine, Neuroscience, Pharmacology +14

Protein kinase C phosphorylates the inhibitory guanine‐nucleotide‐binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

Toshiaki Katada, Alfred G. Gilman, Yasuhiro Watanabe et al. · European Journal of Biochemistry · 1985 · 735 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

R A North, John T. Williams, Annmarie Surprenant et al. · Proceedings of the National Academy of Sciences · 1987 · 618 citations · Full text

Medicine, Neuroscience, Pharmacology +17