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Clinical and Laboratory Evaluation of a New Inhalation Agent: Compound 347 (CHF2-O-CF2-CHF Cl)
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1968
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AsthmaGastroenterologyPleasant InductionAnesthetic AdministrationMedicinal ChemistryRespiratory ToxicologyPulmonary PharmacologyToxicologyChf2-o-cf2-chf ClCompound 347Anesthetic PharmacologyAnesthesia PracticeNitrous Oxide–oxygenPharmacologyPulmonary DiseaseAnaesthetic AgentInhalation ToxicologyNew Inhalation AgentAnesthesiaMedicineAnesthesiology
Compound 347 (CHF2-O-CF2-CHFCl), a new non-explosive fluorinated ether, was administered with nitrous oxide–oxygen to 100 patients for major elective abdominal operations. This agent provided rapid, pleasant induction and emergence and adequate hypnosis, analgesia and muscular relaxation, with minim