Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats

Depression: a new animal model sensitive to antidepressant treatments

Roger D. Porsolt, Manuel Pichon, M Jalfre · Nature · 1977 · 4.4K citations

Psychiatry, Behavioral Neuroscience, Mood Symptom +9

A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

A. Ennaceur, Jean Delacour · Behavioural Brain Research · 1988 · 3.2K citations

Memory Retrieval, Behavioral Neuroscience, Memory Assessment +10

Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant

Paul Willner, Anthony Towell, D. Sampson et al. · Psychopharmacology · 1987 · 1.9K citations

Stress Hormone, Psychiatry, Sucrose Preference +12

Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats

Paul M. Plotsky, Michael J. Meaney · Molecular Brain Research · 1993 · 1.6K citations

Stress Hormone, Neurophysiology, Stress +11

Brain Corticosteroid Receptor Balance in Health and Disease

E. R. de Kloet · Endocrine Reviews · 1998 · 1.2K citations

Medicine, Brain Health, Neuropharmacology +7