A Total Synthesis of (±)-Fendleridine

Abstract

The oxidative cyclization of the aminoalcohol(7)with mercuric acetate gave (+)-fendleridinetla).In this synthetic course, the reduction product of N-tosyl vinylogous amide(2) with lithium aluminum hydride was now further purified, and the former assignment of the structure(4) was revised to be 5, -based upon the chemical and spectroscopic evidences.