Synthesis of 5-substituted-3-[(2′S,3′S)-3′-hydroxy-2′-hydroxymethyltetrahydrofuran-3′-yl]-1,2,4-oxadiazoles and their epimers

Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues.

Shin-Lian Doong, Chi‐Wei Tsai, Raymond F. Schinazi et al. · Proceedings of the National Academy of Sciences · 1991 · 516 citations

Life Sciences, Infectious Diseases, Molecular Biology +16

Nucleosides and Nucleotides

Kazunobu Miura, Masatoshi SHIGA, Tohru Ueda · The Journal of Biochemistry · 1973 · 487 citations

Pharmacy, Biochemistry, Chemistry +15

Synthesis and Biological Evaluation of 2',3'-Dideoxy-L-pyrimidine Nucleosides as Potential Antiviral Agents against Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV)

Tai‐Shun Lin, Mei‐Zhen Luo, Mao‐Chin Liu et al. · Journal of Medicinal Chemistry · 1994 · 156 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure−Activity Relationships of 1-(2-Deoxy-2-fluoro-β-<scp>l</scp>-arabino- furanosyl)pyrimidine Nucleosides as Anti-Hepatitis B Virus Agents

Tianwei Ma, S. Balakrishna Pai, Yong Zhu et al. · Journal of Medicinal Chemistry · 1996 · 141 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Studies on the synthesis and biological activities of 4′-(R)-hydroxy-5′-(S)-hydroxymethyl-tetrahydrofuranyl purines and pyrimidines

Hongwu Yu, Liangren Zhang, Ji‐Chang Zhou et al. · Bioorganic & Medicinal Chemistry · 1996 · 36 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8