Nanometres and piconewtons: the macromolecular mechanics of kinesin

Observation of a single-beam gradient force optical trap for dielectric particles

A. Ashkin, J. M. Dziedzic, J. E. Bjorkholm et al. · Optics Letters · 1986 · 6.9K citations

Photonics, Gradient Force, Optical Materials +15

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

Ron Vale, Thomas S. Reese, Michael P. Sheetz · Cell · 1985 · 2K citations

Protein Function, Macromolecular Machine, Molecular Biology +8

Single myosin molecule mechanics: piconewton forces and nanometre steps

Jeffrey T. Finer, Robert Simmons, James A. Spudich · Nature · 1994 · 1.9K citations

Single Molecule Biophysics, Natural Sciences, Molecular Biology +5

Direct observation of kinesin stepping by optical trapping interferometry

Karel Svoboda, Christoph F. Schmidt, Bruce J. Schnapp et al. · Nature · 1993 · 1.9K citations

Physics, Microscopy, Natural Sciences +6

Forced thermal ratchets

Marcelo O. Magnasco · Physical Review Letters · 1993 · 1.2K citations

Engineering, Stochastic Phenomenon, Heavy Damping +16