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Aerosol mixing in an animal exposure chamber having three levels of caging with excreta pans
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1982
Year
AeroacousticsEngineeringFluid MechanicsConcentration UniformityAir QualityExposure AssessmentAerosol TransportIndoor AerosolAerosol SamplingEnvironmental HealthAnimal Exposure ChamberParticle TechnologyExcreta PansPublic HealthAerosol MixingAir SamplingMultiphase FlowAerosol BuildupAerospace EngineeringEnvironmental EngineeringAerodynamicsIndoor Air QualityAir PollutionUniform Movement
To achieve uniform movement of air within an animal aerosol exposure chamber, and to meet animal husbandry requirements, we modified existing chambers in three ways: 1) air was introduced along the walls of the chamber; 2) catch pans were suspended away from chamber walls (except for the lowest level, which extended to the walls); 3) space between pans was allowed for exhaust flow. Each tier in the chamber acted like a perfectly-mixing box, resulting in clearance half-times of 3 to 6 minutes at a flow of 10 chamber equivalent volumes/hour. Concentration uniformity and aerosol buildup were measured in a full-scale chamber. We also demonstrated that measurements of flow visualization made in a reduced-scale, dynamically similar model were applicable to a full-scale chamber.