Malignant endovascular papillary angioendothelioma of the skin in childhood.Clinicopathologic study of 6 cases

Abstract

This paper describes 6 instances of a peculiar malignant angioendothelioma of the skin in children. Microscopically, the neoplasm is characterized by remarkable, bizarre, intravascular papillary proliferations of atypical endothelium. The tumor is locally invasive and has a potential to metastasize. In spite of this, as far as we know, none of the children have died. All our patients are living and well, free from recurrence and metastases 4 to 16 years after last surgical treatment. The present study was undertaken to demonstrate this curious variant of malignant angioendothelioma in childhood, which has a limited degree of malignancy.