Publication | Closed Access
CADAVER KIDNEY TRANSPLANTS
70
Citations
0
References
1967
Year
Solid Organ TransplantationRenal PathologySurgeryGlomerulonephritisTranslational MedicineGraft SurvivalChronic Kidney DiseaseTransplantation SurgeryHemodialysisTransplantationKidney TransplantKidney FailureTransplant FailureWarm IschemiaEnd-stage Renal DiseaseUrologyKidney TransplantationCadaver OriginTransplant SurgeryCadaver Kidney TransplantsMedicineNephrology
The experience obtained from 59 renal transplantations is presented. In 58 instances the kidney was of cadaver origin. Subsequent function was related to minutes of warm ischemia and there was no difference in late function between those with differing degrees of acute tubular necrosis. The complications and causes of transplant failure are given for 33 failures in 31 patients; at least 10 of these failures were due to the nonimmunologic additional hazards of cadaver kidney transplantation. An analysis of 29 patients, ranked by their evidence of rejection activity in the first three post-transplant months shows significant difference in renal function, hippuran renogram, pathologic changes in glomeruli and vessels, but not interstitial cellular infiltration. There was also a significant difference whereby those with more hemodialysis prior to transplantation showed less evidence of rejection activity. This finding is discussed. Nonrenal complications are described and total survival figures are given.