Journal of Labelled Compounds and Radiopharmaceuticals · 1999 · 68 citations · 0 references
MedicineNuclear MedicinePharmaceuticsPolymer ChemistryRadionuclide TherapyTherapeutic Nuclear MedicineChromatographic PurificationChromatographyRadiopharmaceutical DesignRadiopharmaceutical PreparationRadiopharmaceutical TherapyRadiopharmaceuticalsNo-carrier-added ProductionRadionuclide PurificationRadiopharmaceuticals For Hepatobiliary ImagingRadiotracer PurificationRadiotracer Synthesis
A new method has been developed that produces no-carrier-added [131I]MIBG in ≥90% radiochemical yield and high chemical purity. Isolation and purification are simple involving just filtration and absorption and desorption onto a C18 Sep-Pak™ cartridge. No-carrier-added material should avoid the potential pharmacological side effects accompanying the current method of production. Copyright © 1999 John Wiley & Sons, Ltd.