The Bulletin of Tokyo Dental College · 2013 · 19 citations · 8 references
Natural SciencesBioengineeringMaterials ScienceBiomaterialsBiophysical ChemistrySurface ScienceAdsorption At InterfacesBioceramicsBiomaterial Surface PropertiesProtein AdsorptionSurface AdsorptionZeta PotentialAlbumin AdsorptionBioadsorptionBovine Serum AlbuminElectrophoretic MobilityHydroxyapatiteHydroxyapatite BiomaterialsProtein Adsorption AnalysisZeta Potential Measurement
The aim of the present study was to examine the adsorption of bovine serum albumin (BSA) to hydroxyapatite surfaces by means of zeta potential. The electrophoretic mobility of both hydroxyapatite and BSA were negative, with BSA itself less negative than hydroxyapatite. The zeta potential of the surface of BSA-adsorbed hydroxyapatite was significantly more negative than that of hydroxyapatite alone (p<0.0001). The BSA histogram indicated two negative peaks, and the zeta potential of BSA-adsorbed hydroxyapatite also showed two similar negative peaks. These results suggest that BSA adsorption to hydroxyapatite surfaces is related to electrostatic interaction.
8