Hemolytic Anemia Due to a Defective Teflon Aortic Valve Prosthesis

Abstract

Case Studies1 August 1965Hemolytic Anemia Due to a Defective Teflon Aortic Valve ProsthesisEDWARD D. VINER, M.D., JOHN W. FROST, M.D., F.A.C.P.EDWARD D. VINER, M.D., JOHN W. FROST, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-2-295 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAs the techniques of cardiac surgery have been refined, with the use of various new heart-lung machines and intracardiac prostheses and with the ultimate possibility of a successful artificial heart, increasing attention has been focused on the effect of these devices on the circulating erythrocytes. Transient anemia, one of the manifestations of the "postperfusion" syndrome described by Kreel and associates (1) and Wheeler, Turner, and Scannell (2), is now frequently recognized. After several months, these patients have no evidence of a residual hemolytic process.In sharp contrast are seven reported cases of severe, prolonged intravascular hemolysis after the repair with...References1. KREELZAROFFCANTERKRASNABARNOFSKY ILIJWIID: A syndrome following total body perfusion. Surg. Gynec. Obstet. 111: 317, 1960. MedlineGoogle Scholar2. WHEELERTURNERSCANNELL EOJDJG: Fever, splenomegaly and atypical lymphocytes—a syndrome observed after cardiac surgery utilizing a pump oxygenator. New Eng. J. Med. 266: 454, 1962. CrossrefMedlineGoogle Scholar3. SAYEDDACIEHANDLEYCLELAND HMJVSMWP: Hemolytic anemia of mechanical origin after open heart surgery. Thorax 16: 356, 1961. CrossrefMedlineGoogle Scholar4. VERDONFORRESTERCROSBY TARHWH: Hemolytic anemia after open-heart repair of ostium-primum defects. New Eng. J. Med. 269: 444, 1963. CrossrefMedlineGoogle Scholar5. 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Author, Article, and Disclosure InformationAffiliations: Philadelphia, PennsylvaniaFrom the Hematology Section of the Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pa.Dr. Viner is a Daland Fellow for Research in Clinical Medicine of the American Philosophical Society, and Trainee in Hematology under training grant T1-Am-5228 of the U.S. Public Health Service.Requests for reprints should be addressed to Edward D. Viner, M.D., Pennsylvania Hospital, 8th and Delancy Sts., Philadelphia, Pa. 19107. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByInvestigation of poikilocytic normochromic normocytic anemiaFactors influencing hemolysis in valve prosthesisIntravascular Hemolysis and Consumption Coagulop- Athy in Defective Aortic Valve Prosthesis. 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PALEY, M.D.LEIOMYOSARCOMA OF THE INFERIOR VENA CAVARenal Siderosis Morphology, Etiology, Pathogenesis and Differential Diagnosis 1 August 1965Volume 63, Issue 2Page: 295-301KeywordsAnemiaAortic valveCardiac surgeryCorticosteroid therapyHematology and oncologyHemolytic anemiaMedical servicesThoracic surgery Issue Published: 1 August 1965 PDF DownloadLoading ...