Concepedia

Efficient Reduction of Acyl Chlorides with Zn(BH4)2/<i>N</i>,<i>N</i>,<i>N</i>′,<i>N</i>′-Tetramethylethylenediamine

Hiyoshizo Kotsuki, Yasuyuki Ushio, N. YOSHIMURA, Masamitsu Ochi

Bulletin of the Chemical Society of Japan · 1988 · 21 citations · 12 references

DOIFull text

Open access

Concepts

Abstract

Abstract Aliphatic and aromatic acyl chlorides were efficiently reduced to give the corresponding alcohols when treated with Zn(BH4)2 in the presence of N,N,N′,N′-tetramethylethylenediamine. The reactions with other bases were also examined.

References

12

Forty years of hydride reductions

Herbert C. Brown, S. Krishnamurthy · Tetrahedron · 1979 · 449 citations

, , +4

Reduction of Aldehydes, Ketones and Acid Chlorides by Sodium Borohydride

Saul W. Chaikin, Weldon G. Brown · Journal of the American Chemical Society · 1949 · 350 citations

, , +7

Reduction of Organic Compounds by Lithium Aluminum Hydride. I. Aldehydes, Ketones, Esters, Acid Chlorides and Acid Anhydrides

Robert F. Nystrom, Weldon G. Brown · Journal of the American Chemical Society · 1947 · 295 citations

, , +6

Compounds Related to Podophyllotoxin. XII. Podophyllotoxone, Picropodophyllone and Dehydropodophyllotoxin<sup>1</sup>

Walter J. Gensler, Francis Johnson, A. D. B. Sloan · Journal of the American Chemical Society · 1960 · 191 citations

, , +5

Total synthesis of (.+-.)-antheridium-inducing factor (AAn) of the Fern Anemia phyllitidis. Clarification of stereochemistry

E. J. Corey, Andrew G. Myers · Journal of the American Chemical Society · 1985 · 128 citations

, , +7