EUS-guided tissue sampling: comparison of ”dual sampling” (Trucut biopsy plus FNA) with ”sequential sampling” (Trucut biopsy and then FNA as required)

Abstract

A sequential sampling strategy, in which EUS-guided Trucut biopsy is attempted first, and FNA performed only when Trucut biopsy fails to obtain a macroscopically adequate sample, achieves a diagnostic accuracy of 92 %, with 11 % of patients requiring both sampling procedures.