An Empiric Risk Scoring Tool for Identifying High-Risk Heterosexual HIV-1–Serodiscordant Couples for Targeted HIV-1 Prevention

Abstract

A discrete combination of clinical and behavioral characteristics defines highest risk HIV-1-serodiscordant couples. Discriminating highest risk couples for HIV-1 prevention programs and clinical trials using a validated risk score could improve research efficiency and maximize the impact of prevention strategies for reducing HIV-1 transmission.