Blood · 1998 · 248 citations · 76 references
Life SciencesHematologyImmunologyCell SignalingImmunoregulationInflammationBone Marrow PhysiologyCytokine BiologyCytokine Receptor SignalingCytokine RegulationCytokine SignalingInflammatory SignalingCytokine Signaling In HematopoiesisHematopoietic SignalingHematopoietic Supportive CytokinesInterleukin-6 Mediated Regulation
T HE INTERLEUKIN-6 (IL-6) family of cytokines acts via receptor complexes that contain at least one subunit of the signal transducing protein gp130.[1][1] The family comprises IL-6, IL-11, ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1), leukemia inhibitory factor (LIF), and oncostatin M
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Hisataka Yasuda, Nobuyuki Shima, N. Nakagawa et al. · Proceedings of the National Academy of Sciences · 1998 · 4.3K citations
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
Roy A. Black, Charles T. Rauch, Carl J. Kozlosky et al. · Nature · 1997 · 3.1K citations
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
Tetsuya Taga, Masahiko Hibi, Yuuichi Hirata et al. · Cell · 1989 · 1.4K citations