Lewis Acid–Doped Natural Phosphate: New Catalysts for the One‐Pot Synthesis of 3,4‐Dihydropyrimdin‐2(1 <i>H</i> )‐one

Abstract

Abstract Inexpensive and readily available natural phosphate doped with metal halides is used to efficiently catalyze the three‐component condensation reaction of an aldehyde, a beta‐keto ester, and urea to afford the corresponding dihydropyrimidin‐2(1H)‐ones in high yields.