Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

Jun Wang, S.M. Soisson, Katherine Young et al. · Nature · 2006 · 815 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

The Transcriptional Responses of Mycobacterium tuberculosis to Inhibitors of Metabolism

Helena I. Boshoff, Timothy G. Myers, Brent R. Copp et al. · Journal of Biological Chemistry · 2004 · 625 citations · Full text

Life Sciences, Microbiology, Molecular Biology +15

The salicylate-derived mycobactin siderophores of <i>Mycobacterium tuberculosis</i> are essential for growth in macrophages

James J. De Voss, K. Rutter, Benjamin G. Schroeder et al. · Proceedings of the National Academy of Sciences · 2000 · 527 citations · Full text

Life Sciences, Microbiology, Molecular Biology +13

Antitrypanosomal and Antileishmanial Activities of Flavonoids and Their Analogues: In Vitro, In Vivo, Structure-Activity Relationship, and Quantitative Structure-Activity Relationship Studies

Deniz Taşdemir, Marcel Kaiser, Reto Brun et al. · Antimicrobial Agents and Chemotherapy · 2006 · 515 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Bacterial Fatty Acid Biosynthesis: Targets for Antibacterial Drug Discovery

John W. Campbell, John E. Cronan · Annual Review of Microbiology · 2001 · 479 citations

Life Sciences, Microbiology, Pharmacology +17