Selenomethionine Prevents Degeneration Induced by Overexpression of Wild-Type Human α-Synuclein during Differentiation of Neuroblastoma Cells

Abstract

Data suggested that Overexpression of wild-type human alpha-synuclein-decreased viability and increased the levels of degenerative changes during differentiation of NB cells were reduced by selenomethionine treatment. This suggest that one of mechanisms of action alpha-synuclein may involve increased oxidative stress.