Concepedia

Inhibition of Dengue virus and West Nile virus proteases by click chemistry-derived benz[d]isothiazol-3(2H)-one derivatives

Kok-Chuan Tiew, Dengfeng Dou, T Teramoto, Huiguo Lai, Kevin R. Alliston, Gerald H. Lushington, R. Padmanabhan, William C. Groutas

Bioorganic & Medicinal Chemistry · 2011 · 71 citations · 27 references

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27

On the size of the active site in proteases. I. Papain

Israël Schechter, Arieh Berger · Biochemical and Biophysical Research Communications · 1967 · 5.2K citations

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Surflex:  Fully Automatic Flexible Molecular Docking Using a Molecular Similarity-Based Search Engine

Ajay N. Jain · Journal of Medicinal Chemistry · 2003 · 1.4K citations

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A Specific Mechanism of Nonspecific Inhibition

Susan L. McGovern, Brian T. Helfand, Brian Y. Feng et al. · Journal of Medicinal Chemistry · 2003 · 605 citations · Full text

, , +17

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus

P. Erbel, Nikolaus Schiering, A. D’Arcy et al. · Nature Structural & Molecular Biology · 2006 · 575 citations

, , +16

A detergent-based assay for the detection of promiscuous inhibitors

Brian Y. Feng, Brian K. Shoichet · Nature Protocols · 2006 · 436 citations · Full text

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