Concepedia

Publication | Open Access

Efficacy of a novel histone deacetylase inhibitor in murine models of hepatocellular carcinoma

DOIFull Paper Access

90

Citations

28

References

2007

Year

Yen‐Shen Lu, Yoko Kashida, Samuel K. Kulp, Yu-Chieh Wang, Dasheng Wang, Jui‐Hsiang Hung, Mónica Tang, Zhong-Zhe Lin, Te-Jung Chen, Ann‐Lii Cheng,
Hepatology

Abstract

OSU-HDAC42 is a potent, orally bioavailable inhibitor of HDAC with a broad spectrum of antitumor activity that includes targets regulating multiple aspects of cancer cell survival. These results suggest that OSU-HDAC42 has clinical value in therapeutic strategies for HCC.

References

YearCitations

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