Tumor necrosis factor α, interleukin‐6 and interleukin‐10 polymorphisms in preeclampsia

Abstract

Because women with IL-10 (-1082) AA genotype have 3.38-fold increased risk of developing PE according to GG genotype (95% CI 1.21-9.4, P = 0.01), we suggest that IL-10 (-1082) variant A allele is associated with an increased risk of preeclampsia, which is independent from its metabolic effects.