Disseminated Vaccinia in a Military Recruit with Human Immunodeficiency Virus (HIV) Disease

Abstract

LIVE-VIRUS vaccines have been well recognized as a cause of severe complications when inadvertently administered to recipients with impaired immunologic function.1 The acquired immunodeficiency syndrome (AIDS) has been recognized as a severe immunodeficiency state caused by infection with a retrovirus, human immunodeficiency virus (HIV).2 HIV infection and disease include a wide spectrum of clinical presentations, such as asymptomatic infections, chronic generalized lymphadenopathy, and frank T-cell deficiency (AIDS-related complex and AIDS).3 Although the natural history of HIV infection has only been partly defined, it is clear that patients with AIDS represent only a minority of the total number of T-cell–deficient patients . . .