A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines

Recent applications of multicomponent reactions in medicinal chemistry

Paul Slobbe, Eelco Ruijter, Romano V. A. Orrù · MedChemComm · 2012 · 476 citations

Pharmacy, Chemistry, Medicinal Chemistry +9

Single step synthesis of new fused pyrimidine derivatives and their evaluation as potent Aurora-A kinase inhibitors

Mohamed R. Shaaban, Tamer S. Saleh, Abdelrahman S. Mayhoub et al. · European Journal of Medicinal Chemistry · 2011 · 75 citations · Full text

Medicine, Medicinal Chemistry, Oncology +12

Dotting the i's in three-component Biginelli-like condensations using 3-amino-1,2,4-triazole as a 1,3-binucleophile

Yuriy V. Sedash, Nikolay Yu. Gorobets, Irina S. Konovalova et al. · RSC Advances · 2012 · 55 citations

Natural Sciences, Chemistry, Organic Chemistry +4

Synthesis of 5,7-Diamino[1,2,4]triazolo[1,2-a][1,3,5]triazines via Annulation of 1,3,5-Triazine Ring onto 3(5)-Amino-1,2,4-triazoles

Wai‐Keung Chui, Anton V. Dolzhenko, Anna V. Dolzhenko · Heterocycles · 2007 · 50 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +10

1,2,4-Triazolo[1,5-a][1,3,5]triazines (5-Azapurines): Synthesis and Biological Activity

Wai‐Keung Chui, Anton V. Dolzhenko, Anna V. Dolzhenko · Heterocycles · 2006 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14