Synthesis and discovery of novel hexacyclic cage compounds as inhibitors of acetylcholinesterase

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.6K citations

Biochemistry, Acetylcholinesterase Activity, Medicine +4

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

Elaine K. Perry, B. E. Tomlinson, G. Blessed et al. · BMJ · 1978 · 2K citations · Full text

Cubanes: Starting Materials for the Chemistry of the 1990s and the New Century

Philip E. Eaton · Angewandte Chemie International Edition in English · 1992 · 356 citations

Chemical Engineering, Saturated Radical, Cubane Chemistry +10

Novel three-component domino reactions of ketones, isatin and amino acids: Synthesis and discovery of antimycobacterial activity of highly functionalised novel dispiropyrrolidines

Raju Suresh Kumar, Michael Rajesh Stephen, Subbu Perumal et al. · European Journal of Medicinal Chemistry · 2009 · 144 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Bioorganic Chemistry +11

Substituted spiro [2.3′] oxindolespiro [3.2″]-5,6-dimethoxy-indane-1″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase

Mohamed Ashraf Ali, Rusli Ismail, Tan Soo Choon et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 137 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Bioorganic Chemistry +8