Concepedia

Mutagen-directed Attenuation of Rift Valley Fever Virus as a Method for Vaccine Development

H. Caplen, C. J. Peters, D. H. L. Bishop

Journal of General Virology · 1985 · 281 citations · 9 references

DOI

Abstract

Serial mutagenesis with 5-fluorouracil has been employed to derive an attenuated strain of Rift Valley fever virus for use as a live virus vaccine.

References

9

A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12

Linda Reed, Hugo Muench · American Journal of Epidemiology · 1938 · 20K citations

, , +27

A simple method of estimating fifty per cent end-points.

Linda Reed · Medical Entomology and Zoology · 1938 · 930 citations

, , +6

Rift Valley fever; the neurotropic adaptation of the virus and the experimental use of this modified virus as a vaccine.

Smithburn Kc · PubMed · 1949 · 163 citations · Full text

, , +9

Rift valley fever.

Easterday Bc · PubMed · 1965 · 135 citations

, , +3

Hydrops amnii in sheep associated with hydranencephaly and arthrogryposis with wesselsbron disease and rift valley fever viruses as aetiological agents.

Jacobus A.W. Coetzer, B.J.H. Barnard · PubMed · 1977 · 101 citations

, , +20