A placebo‐controlled, random‐assignment, parallel‐group pilot study of adjunctive topiramate for patients with schizoaffective disorder, bipolar type

Abstract

This pilot study did not support clinical efficacy for adjunctive topiramate treatment in patients with SAD-BT. There were no major safety or tolerability issues in this study. Confirming the results of other studies, topiramate-treated patients did experience greater body weight loss and reduction in BMI.