Disturbed ratio of renal 20-HETE/EETs is involved in androgen-induced hypertension in cytochrome P450 4F2 transgenic mice

Formation of 20-Hydroxyeicosatetraenoic Acid, a Vasoactive and Natriuretic Eicosanoid, in Human Kidney

Jerome M. Lasker, W.Bill Chen, Imre Wolf et al. · Journal of Biological Chemistry · 2000 · 304 citations · Full text

Medicine, Nephrology, Drug Metabolism +16

Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension

Vijaykumar Holla, Fadi Adas, John D. Imig et al. · Proceedings of the National Academy of Sciences · 2001 · 244 citations · Full text

Medicine, Endocrinology, Physiology +17

Functional Variant of <i>CYP4A11</i> 20-Hydroxyeicosatetraenoic Acid Synthase Is Associated With Essential Hypertension

James V. Gainer, Aouatef Bellamine, Elliott P. Dawson et al. · Circulation · 2004 · 198 citations

Medicine, Biochemistry, Pharmacology +15

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation

Dominik N. Müller, Cosima Schmidt, Eduardo Barbosa‐Sicard et al. · Biochemical Journal · 2007 · 173 citations · Full text

Medicine, Biochemistry, Pharmacology +14

Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II

Magdalena Alonso‐Galicia, Kristopher G. Maier, Andrew S. Greene et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2002 · 151 citations

Medicine, Cardiology, Pharmacology +15