Effects of Hypothermia on Halothane MAC and Isoflurane MAC in the Rat

Abstract

MAC was determined in tracheotomized rats for halothane (5 rats) and inoflurane (3 rats) at 37, 32, and 27 C. Rectilinear decreases in MAC occurred with both agents. The change with halothane (4.82 per cent per degree) did not differ significantly from that seen with isoflurane (5.28 per cent per de