The Absolute Configurations of the α- and β-Methylcholine Isomers and Their Acetyl and Succinyl Esters

Abstract

Abstract The absolute configurations of the (+)-acetyl-α- and -β-methyl-choline iodides have been established, being related to D(−)-alanine hydrochloride and L(+)-lactic acid respectively. The (+)-, (−)- and racemic forms of the precursor amino-alcohols have been converted to the succinyl esters and these quaternised.