Solubility of Lovastatin in Acetone, Methanol, Ethanol, Ethyl Acetate, and Butyl Acetate between 283 K and 323 K

Abstract

The solubilities of lovastatin in acetone, methanol, ethanol, ethyl acetate, and butyl acetate between 283 K and 323 K were measured using a synthetic method. A laser monitoring observation technique was used to determine the disappearance of the solid phase in a solid + liquid mixture. The experimental solubility data was correlated with an empirical equation.