Immunohistochemical analysis of matrix metalloproteinases (1, 2, and 9), <scp>K</scp>i‐67, and myofibroblasts in keratocystic odontogenic tumors and pericoronal follicles

Abstract

MMP-1, MMP-9, and proliferative activity appear to play important roles in KCOT pathogenesis. The increased proliferative activity with KCOT was associated with elevated MMP-1 production in the parenchyma, which influenced the growth of the lesion in association with an increased number of MFs.